Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

During development, the retinal vasculature grows toward hypoxic areas in an organized fashion. By contrast, in ischemic retinopathies, new blood vessels grow out of the retinal surfaces without ameliorating retinal hypoxia. Restoration of proper angiogenic directionality would be of great benefit t...

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Détails bibliographiques
Auteurs principaux: Fukushima, Yoko, Okada, Mitsuhiro, Kataoka, Hiroshi, Hirashima, Masanori, Yoshida, Yutaka, Mann, Fanny, Gomi, Fumi, Nishida, Kohji, Nishikawa, Shin-Ichi, Uemura, Akiyoshi
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083763/
https://ncbi.nlm.nih.gov/pubmed/21505259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44900
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