Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

During development, the retinal vasculature grows toward hypoxic areas in an organized fashion. By contrast, in ischemic retinopathies, new blood vessels grow out of the retinal surfaces without ameliorating retinal hypoxia. Restoration of proper angiogenic directionality would be of great benefit t...

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Detalhes bibliográficos
Main Authors: Fukushima, Yoko, Okada, Mitsuhiro, Kataoka, Hiroshi, Hirashima, Masanori, Yoshida, Yutaka, Mann, Fanny, Gomi, Fumi, Nishida, Kohji, Nishikawa, Shin-Ichi, Uemura, Akiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083763/
https://ncbi.nlm.nih.gov/pubmed/21505259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44900
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