Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

During development, the retinal vasculature grows toward hypoxic areas in an organized fashion. By contrast, in ischemic retinopathies, new blood vessels grow out of the retinal surfaces without ameliorating retinal hypoxia. Restoration of proper angiogenic directionality would be of great benefit t...

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Autores principales: Fukushima, Yoko, Okada, Mitsuhiro, Kataoka, Hiroshi, Hirashima, Masanori, Yoshida, Yutaka, Mann, Fanny, Gomi, Fumi, Nishida, Kohji, Nishikawa, Shin-Ichi, Uemura, Akiyoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083763/
https://ncbi.nlm.nih.gov/pubmed/21505259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44900
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