S-Adenosyl-l-methionine Induces Compaction of Nascent Peptide Chain inside the Ribosomal Exit Tunnel upon Translation Arrest in the Arabidopsis CGS1 Gene

Expression of the Arabidopsis CGS1 gene, encoding the first committed enzyme of methionine biosynthesis, is feedback-regulated in response to S-adenosyl-l-methionine (AdoMet) at the mRNA level. This regulation is first preceded by temporal arrest of CGS1 translation elongation at the Ser-94 codon. A...

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Détails bibliographiques
Auteurs principaux: Onoue, Noriyuki, Yamashita, Yui, Nagao, Nobuhiro, Goto, Derek B., Onouchi, Hitoshi, Naito, Satoshi
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083191/
https://ncbi.nlm.nih.gov/pubmed/21335553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211656
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