S-Adenosyl-l-methionine Induces Compaction of Nascent Peptide Chain inside the Ribosomal Exit Tunnel upon Translation Arrest in the Arabidopsis CGS1 Gene

Expression of the Arabidopsis CGS1 gene, encoding the first committed enzyme of methionine biosynthesis, is feedback-regulated in response to S-adenosyl-l-methionine (AdoMet) at the mRNA level. This regulation is first preceded by temporal arrest of CGS1 translation elongation at the Ser-94 codon. A...

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Detalhes bibliográficos
Main Authors: Onoue, Noriyuki, Yamashita, Yui, Nagao, Nobuhiro, Goto, Derek B., Onouchi, Hitoshi, Naito, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083191/
https://ncbi.nlm.nih.gov/pubmed/21335553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211656
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