Ribosomes in a Stacked Array: ELUCIDATION OF THE STEP IN TRANSLATION ELONGATION AT WHICH THEY ARE STALLED DURING S-ADENOSYL-l-METHIONINE-INDUCED TRANSLATION ARREST OF CGS1 mRNA

Expression of CGS1, which codes for an enzyme of methionine biosynthesis, is feedback-regulated by mRNA degradation in response to S-adenosyl-l-methionine (AdoMet). In vitro studies revealed that AdoMet induces translation arrest at Ser-94, upon which several ribosomes stack behind the arrested one,...

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Detalhes bibliográficos
Main Authors: Yamashita, Yui, Kadokura, Yoshitomo, Sotta, Naoyuki, Fujiwara, Toru, Takigawa, Ichigaku, Satake, Akiko, Onouchi, Hitoshi, Naito, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007459/
https://ncbi.nlm.nih.gov/pubmed/24652291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526616
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