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Mitochondrial Cu,Zn-Superoxide Dismutase Mediates Pulmonary Fibrosis by Augmenting H(2)O(2) Generation

The release of H(2)O(2) from alveolar macrophages has been linked to the development of pulmonary fibrosis, but little is known about its source or mechanism of production. We found that alveolar macrophages from asbestosis patients spontaneously produce high levels of H(2)O(2) and have high express...

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Bibliografiset tiedot
Päätekijät: He, Chao, Murthy, Shubha, McCormick, Michael L., Spitz, Douglas R., Ryan, Alan J., Carter, A. Brent
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083152/
https://ncbi.nlm.nih.gov/pubmed/21393238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.187377
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