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Bacterial Toxin RelE Mediates Frequent Codon-independent mRNA Cleavage from the 5′ End of Coding Regions in Vivo

The enzymatic activity of the RelE bacterial toxin component of the Escherichia coli RelBE toxin-antitoxin system has been extensively studied in vitro and to a lesser extent in vivo. These earlier reports revealed that 1) RelE alone does not exhibit mRNA cleavage activity, 2) RelE mediates mRNA cle...

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Hlavní autoři: Hurley, Jennifer M., Cruz, Jonathan W., Ouyang, Ming, Woychik, Nancy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083149/
https://ncbi.nlm.nih.gov/pubmed/21324908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108969
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