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Cys−Cys Cross-Linking Shows Contact between the N-Terminus of Lethal Factor and Phe427 of the Anthrax Toxin Pore

[Image: see text] Electrophysiological studies of wild-type and mutated forms of anthrax protective antigen (PA) suggest that the Phe clamp, a structure formed by the Phe427 residues within the lumen of the oligomeric PA pore, binds the unstructured N-terminus of the lethal factor and the edema fact...

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Detalhes bibliográficos
Main Authors: Janowiak, Blythe E., Jennings-Antipov, Laura D., Collier, R. John
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082969/
https://ncbi.nlm.nih.gov/pubmed/21425869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1017446
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