GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore

We analyzed the 440-kDa transmembrane pore formed by the protective antigen (PA) moiety of anthrax toxin in the presence of GroEL by negative-stain electron microscopy. GroEL binds both the heptameric PA prepore and the PA pore. The latter interaction retards aggregation of the pore, prolonging its...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Katayama, Hiroo, Janowiak, Blythe E, Brzozowski, Marek, Juryck, Jordan, Falke, Scott, Gogol, Edward P, Collier, R John, Fisher, Mark T
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504863/
https://ncbi.nlm.nih.gov/pubmed/18568038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1442
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker