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Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides

Mutation-based treatments are a new development in genetic medicine, in which the nature of the mutation dictates the therapeutic strategy. Interest has recently focused on diseases caused by premature termination codons (PTCs). Drugs inducing the readthrough of these PTCs restore the production of...

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Bibliografiske detaljer
Main Authors: Floquet, Célia, Deforges, Jules, Rousset, Jean-Pierre, Bidou, Laure
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082906/
https://ncbi.nlm.nih.gov/pubmed/21149266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1277
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