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In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation.
Antisense and triplex oligonucleotides continue to demonstrate potential as mediators of gene-specific repression of protein synthesis. However, inefficient and heterogeneous cellular uptake, intracellular sequestration, and rapid intracellular and extracellular degradation represent obstacles to th...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
1994
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| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052538/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.14.2830 |
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