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A novel fluorogenic substrate for ribonucleases. Synthesis and enzymatic characterization.

The synthesis and enzymatic characterization of DUPAAA, a novel fluorogenic substrate for RNases of the pancreatic type is described. It consists of the dinucleotide uridylyl-3',5'-deoxyadenosine to which a fluorophore, o-aminobenzoic acid, and a quencher, 2,4-dinitroaniline, have been att...

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Detalhes bibliográficos
Main Authors: Zelenko, O, Neumann, U, Brill, W, Pieles, U, Moser, H E, Hofsteenge, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC308241/
https://ncbi.nlm.nih.gov/pubmed/8052528
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