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p120 catenin is required for normal renal tubulogenesis and glomerulogenesis

Defects in the development or maintenance of tubule diameter correlate with polycystic kidney disease. Here, we report that absence of the cadherin regulator p120 catenin (p120ctn) from the renal mesenchyme prior to tubule formation leads to decreased cadherin levels with abnormal morphologies of ea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marciano, Denise K., Brakeman, Paul R., Lee, Chao-Zong, Spivak, Natalie, Eastburn, Dennis J., Bryant, David M., Beaudoin, Gerard M., Hofmann, Ilse, Mostov, Keith E., Reichardt, Louis F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082309/
https://ncbi.nlm.nih.gov/pubmed/21521738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.056564
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