SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling

The essential roles of SHH in anteroposterior (AP) and AER-FGF signalling in proximodistal (PD) limb bud development are well understood. In addition, these morphoregulatory signals are key components of the self-regulatory SHH/GREM1/AER-FGF feedback signalling system that regulates distal progressi...

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Autores principales: Probst, Simone, Kraemer, Conradin, Demougin, Philippe, Sheth, Rushikesh, Martin, Gail R., Shiratori, Hidetaka, Hamada, Hiroshi, Iber, Dagmar, Zeller, Rolf, Zuniga, Aimée
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2011
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082298/
https://ncbi.nlm.nih.gov/pubmed/21471156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063966
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