If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice

Hyperglycemia and hyperinsulinemia accelerate both aging and cancer. Antidiabetic biguanides such as metformin decrease glucose, insulin and IGF-1 level. Metformin increases lifespan and prevents cancer in mice, although its effects vary, depending on mice strain and gender. Here we showed that chro...

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Библиографические подробности
Главные авторы: Anisimov, Vladimir N., Berstein, Lev M., Popovich, Irina G., Zabezhinski, Mark A., Egormin, Peter A., Piskunova, Tatiana S., Semenchenko, Anna V., Tyndyk, Margarita L., Yurova, Maria N., Kovalenko, Irina G., Poroshina, Tatiana E.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2011
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082009/
https://ncbi.nlm.nih.gov/pubmed/21386129
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