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NCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genes
CYP2Cs and CYP3A4 sub family of enzymes of the Cytochrome P-450 super family metabolize clinically prescribed therapeutics. Constitutive and induced expressions of these enzymes are under the control of HNF4α and rifampicin activated PXR. In the present study, we show a mechanism for ligand dependen...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082001/ https://ncbi.nlm.nih.gov/pubmed/21292004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2011.01.013 |
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