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Development of Targeted Recombinant Polymers that can deliver siRNA to the Cytoplasm and Plasmid DNA to the Cell Nucleus

One of the major limitations to effective siRNA delivery is the lack of a siRNA-specific delivery system. Currently, the same delivery systems that are used for plasmid DNA (pDNA) delivery to the cell nucleus are used for siRNA delivery to the cytoplasm. To fill this gap, the objective of this study...

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Detalhes bibliográficos
Main Authors: Canine, Brenda F., Wang, Yuhua, Ouyang, Wenyun, Hatefi, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081961/
https://ncbi.nlm.nih.gov/pubmed/21192992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.12.011
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