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Biosynthesis and characterization of a novel genetically engineered polymer for targeted gene transfer to cancer cells
A novel multi-domain biopolymer was designed and genetically engineered with the purpose to target and transfect cancer cells. The biopolymer contains at precise locations: 1) repeating units of arginine and histidine to condense pDNA and lyse endosome membranes, 2) a HER2 targeting affibody to targ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920211/ https://ncbi.nlm.nih.gov/pubmed/19379785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.04.017 |
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