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Biosynthesis and characterization of a novel genetically engineered polymer for targeted gene transfer to cancer cells

A novel multi-domain biopolymer was designed and genetically engineered with the purpose to target and transfect cancer cells. The biopolymer contains at precise locations: 1) repeating units of arginine and histidine to condense pDNA and lyse endosome membranes, 2) a HER2 targeting affibody to targ...

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Sonraí Bibleagrafaíochta
Main Authors: Canine, Brenda. F., Wang, Yuhua, Hatefi, Arash
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920211/
https://ncbi.nlm.nih.gov/pubmed/19379785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.04.017
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