Opioid Receptor Probes Derived from Cycloaddition of the Hallucinogen Natural Product Salvinorin A

As part of our continuing efforts toward more fully understanding the structure-activity relationships of the neoclerodane diterpene salvinorin A, we report the synthesis and biological characterization of unique cycloadducts through [4+2] Diels-Alder cycloaddition. Microwave-assisted methods were d...

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Autori principali: Lozama, Anthony, Cunningham, Christopher W., Caspers, Michael J., Douglas, Justin T., Dersch, Christina M., Rothman, Richard B., Prisinzano, Thomas E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081938/
https://ncbi.nlm.nih.gov/pubmed/21338114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np1007872
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