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Discrimination of methylcytosine from hydroxymethylcytosine in DNA molecules
Modified DNA bases are widespread in biology. 5-Methylcytosine (mC) is a predominant epigenetic marker in higher eukaryotes involved in gene regulation, development, aging, cancer, and disease. Recently, 5-hydroxymethylcytosine (hmC) was identified in mammalian brain tissue and stem cells. However,...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081508/ https://ncbi.nlm.nih.gov/pubmed/21155562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107836t |
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