Matrix Metalloproteinase Activity Causes VEGFR-2 Cleavage and Microvascular Rarefaction in Rat Mesentery

A complication of the spontaneously hypertensive rat (SHR) is microvascular rarefaction, defined by the loss of microvessels. However, the molecular mechanisms involved in this process remain incompletely identified. Recent work in our laboratory suggests that matrix metalloproteinases (MMPs) may pl...

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Bibliographic Details
Main Authors: Tran, Edward D., Yang, Ming, Chen, Andrew, DeLano, Frank A., Murfee, Walter L., Schmid-Schönbein, Geert W.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081385/
https://ncbi.nlm.nih.gov/pubmed/21418372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1549-8719.2011.00082.x
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