Direct detection of nucleic acid hybridization on the surface of a charge coupled device.

A method is described for the detection of DNA hybrids formed on a solid support, based upon the pairing of oligonucleotide chemistry and the technologies of electronic microdevice design. Surface matrices have been created in which oligonucleotide probes are covalently linked to a thin SiO2 film. 3...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Lamture, J B, Beattie, K L, Burke, B E, Eggers, M D, Ehrlich, D J, Fowler, R, Hollis, M A, Kosicki, B B, Reich, R K, Smith, S R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1994
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8029021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.11.2121
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