Direct detection of nucleic acid hybridization on the surface of a charge coupled device.
A method is described for the detection of DNA hybrids formed on a solid support, based upon the pairing of oligonucleotide chemistry and the technologies of electronic microdevice design. Surface matrices have been created in which oligonucleotide probes are covalently linked to a thin SiO2 film. 3...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1994
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8029021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.11.2121 |
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