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Dermatan Sulfate Interacts with Dead Cells and Regulates CD5(+) B-Cell Fate: Implications for a Key Role in Autoimmunity
CD5(+) (B-1a) B cells play pivotal roles in autoimmunity through expression of autoreactive B-cell receptors and production of autoantibodies. The mechanism underlying their positive selection and expansion is currently unknown. This study demonstrates that dermatan sulfate (DS) expands the B-1a cel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081202/ https://ncbi.nlm.nih.gov/pubmed/21514431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.028 |
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