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Human Proteins with Affinity for Dermatan Sulfate Have the Propensity to Become Autoantigens

The mystery of why and how a small, seemingly disparate subset of all self molecules become functional autoantigens holds a key to understanding autoimmune diseases. Here and in a companion article in this issue, we show that affinity of self molecules to the glycosaminoglycan dermatan sulfate (DS)...

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Autors principals: Rho, Jung-hyun, Zhang, Wei, Murali, Mandakolathur, Roehrl, Michael H.A., Wang, Julia Y.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081203/
https://ncbi.nlm.nih.gov/pubmed/21514432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.031
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