Skp2 Overexpression Is Associated with Loss of BRCA2 Protein in Human Prostate Cancer

BRCA2 (breast cancer 2, early onset) is a tumor suppressor gene that confers increased susceptibility for prostate cancer (PCa). Previous in vitro experiments demonstrated that Skp2, an E3 ubiquitin ligase aberrantly overexpressed in PCa, is involved in the proteolytic degradation of BRCA2 in PCa ce...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Arbini, Arnaldo A., Greco, Margherita, Yao, Jorge L., Bourne, Patricia, Marra, Ersilia, Hsieh, Jer-Tsong, di Sant'Agnese, Paul A., Moro, Loredana
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2011
विषय:
Regular Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081144/
https://ncbi.nlm.nih.gov/pubmed/21514447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.050
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