Mitochondrial DNA Depletion Reduces PARP-1 Levels and Promotes Progression of the Neoplastic Phenotype in Prostate Carcinoma

Mitochondrial dysfunction resulting from mitochondrial DNA (mtDNA) mutations and/or depletion has been correlated with cancer progression and drug resistance. To investigate the role of mtDNA in prostate cancer progression, we used LNCaP and PC-3 prostate carcinoma cells as experimental model. Compa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Oncol
Main Authors: Moro, Loredana, Arbini, Arnaldo A., Marra, Ersilia, Greco, Margherita
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2008
Assuntos:
Other
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618976/
https://ncbi.nlm.nih.gov/pubmed/18607066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2008-0427
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados