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Mitochondrial DNA Depletion Reduces PARP-1 Levels and Promotes Progression of the Neoplastic Phenotype in Prostate Carcinoma

Mitochondrial dysfunction resulting from mitochondrial DNA (mtDNA) mutations and/or depletion has been correlated with cancer progression and drug resistance. To investigate the role of mtDNA in prostate cancer progression, we used LNCaP and PC-3 prostate carcinoma cells as experimental model. Compa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Oncol
Egile Nagusiak: Moro, Loredana, Arbini, Arnaldo A., Marra, Ersilia, Greco, Margherita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: IOS Press 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618976/
https://ncbi.nlm.nih.gov/pubmed/18607066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2008-0427
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