Skp2 Overexpression Is Associated with Loss of BRCA2 Protein in Human Prostate Cancer

BRCA2 (breast cancer 2, early onset) is a tumor suppressor gene that confers increased susceptibility for prostate cancer (PCa). Previous in vitro experiments demonstrated that Skp2, an E3 ubiquitin ligase aberrantly overexpressed in PCa, is involved in the proteolytic degradation of BRCA2 in PCa ce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Arbini, Arnaldo A., Greco, Margherita, Yao, Jorge L., Bourne, Patricia, Marra, Ersilia, Hsieh, Jer-Tsong, di Sant'Agnese, Paul A., Moro, Loredana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081144/
https://ncbi.nlm.nih.gov/pubmed/21514447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.050
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados