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Skp2 Overexpression Is Associated with Loss of BRCA2 Protein in Human Prostate Cancer
BRCA2 (breast cancer 2, early onset) is a tumor suppressor gene that confers increased susceptibility for prostate cancer (PCa). Previous in vitro experiments demonstrated that Skp2, an E3 ubiquitin ligase aberrantly overexpressed in PCa, is involved in the proteolytic degradation of BRCA2 in PCa ce...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Investigative Pathology
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081144/ https://ncbi.nlm.nih.gov/pubmed/21514447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.050 |
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