Skp2 Overexpression Is Associated with Loss of BRCA2 Protein in Human Prostate Cancer

BRCA2 (breast cancer 2, early onset) is a tumor suppressor gene that confers increased susceptibility for prostate cancer (PCa). Previous in vitro experiments demonstrated that Skp2, an E3 ubiquitin ligase aberrantly overexpressed in PCa, is involved in the proteolytic degradation of BRCA2 in PCa ce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Arbini, Arnaldo A., Greco, Margherita, Yao, Jorge L., Bourne, Patricia, Marra, Ersilia, Hsieh, Jer-Tsong, di Sant'Agnese, Paul A., Moro, Loredana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2011
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081144/
https://ncbi.nlm.nih.gov/pubmed/21514447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.01.050
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