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Selection of novel forms of a functional domain within the Tetrahymena ribozyme.

P5abc is an RNA structure within the self-splicing Tetrahymena group I intron that provides an activation function to the remainder of the ribozyme, either when present in cis or when added in trans. This 69-nucleotide activator domain was replaced with randomized sequence of 20 or 40 nt in length,...

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Autores principales: Williams, K P, Imahori, H, Fujimoto, D N, Inoue, T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC308113/
https://ncbi.nlm.nih.gov/pubmed/8029006
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