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Selection of novel forms of a functional domain within the Tetrahymena ribozyme.
P5abc is an RNA structure within the self-splicing Tetrahymena group I intron that provides an activation function to the remainder of the ribozyme, either when present in cis or when added in trans. This 69-nucleotide activator domain was replaced with randomized sequence of 20 or 40 nt in length,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1994
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC308113/ https://ncbi.nlm.nih.gov/pubmed/8029006 |
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