Impaired Interferon Signaling in Dendritic Cells From Older Donors Infected In Vitro With West Nile Virus

West Nile virus (WNV), a mosquito-borne, single-stranded RNA flavivirus, causes significant human morbidity and mortality in the older population; thus, we investigated the effects of aging on infection with WNV in dendritic cells (DCs). We infected DCs with WNV in vitro and quantified cytokines and...

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Autori principali: Qian, Feng, Wang, Xiaomei, Zhang, Lin, Lin, Aiping, Zhao, Hongyu, Fikrig, Erol, Montgomery, Ruth R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080893/
https://ncbi.nlm.nih.gov/pubmed/21398396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir048
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