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Impaired Interferon Signaling in Dendritic Cells From Older Donors Infected In Vitro With West Nile Virus
West Nile virus (WNV), a mosquito-borne, single-stranded RNA flavivirus, causes significant human morbidity and mortality in the older population; thus, we investigated the effects of aging on infection with WNV in dendritic cells (DCs). We infected DCs with WNV in vitro and quantified cytokines and...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080893/ https://ncbi.nlm.nih.gov/pubmed/21398396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir048 |
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