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In Autoimmune Diabetes Unique Autoreactive T Cells Recognize Insulin Peptides Generated in the Islets of Langerhans

Besides the genetic framework, there are two critical requirements for the development of tissue-specific autoimmune diseases. First, autoreactive T cells need to escape thymic negative selection. Second, they need to find suitable conditions for autoantigen presentation and activation in the target...

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Bibliografski detalji
Glavni autori: Mohan, James F., Levisetti, Matteo G., Calderon, Boris, Herzog, Jeremy W., Petzold, Shirley J., Unanue, Emil R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080751/
https://ncbi.nlm.nih.gov/pubmed/20190756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1850
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