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Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine

BACKGROUND: α(2A)-Adrenoceptors (α(2A)-ARs) have important roles in sympathetic cardiovascular regulation. Variants of ADRA2A affect gene transcription and expression and are associated with insulin release and risk for type 2 diabetes. We examined whether ADRA2A variants are also associated with ca...

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Detalhes bibliográficos
Main Authors: Kurnik, Daniel, Muszkat, Mordechai, Li, Chun, Sofowora, Gbenga G., Friedman, Eitan A., Scheinin, Mika, Wood, Alastair J. J., Stein, C. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080459/
https://ncbi.nlm.nih.gov/pubmed/21325151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.110.957662
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