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Variation in the α(2A)-adrenoceptor gene and the effect of dexmedetomidine on plasma insulin and glucose
OBJECTIVES: Sympathetic activation inhibits insulin secretion through activation of pancreatic α(2A)-adrenoreceptors (α(2A)ARs). A common genetic α(2A)AR variant (rs553668) is associated with impaired insulin secretion. α(2)AR-agonists would be expected to decrease insulin secretion, but their effec...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787837/ https://ncbi.nlm.nih.gov/pubmed/23873118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283642f93 |
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