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LARGE Expression Augments the Glycosylation of Glycoproteins in Addition to α-Dystroglycan Conferring Laminin Binding

Mutations in genes encoding glycosyltransferases (and presumed glycosyltransferases) that affect glycosylation and extracellular matrix binding activity of α-dystroglycan (α-DG) cause congenital muscular dystrophies (CMDs) with central nervous system manifestations. Among the identified genes, LARGE...

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Detalhes bibliográficos
Main Authors: Zhang, Zhen, Zhang, Peng, Hu, Huaiyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080415/
https://ncbi.nlm.nih.gov/pubmed/21533062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019080
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