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Generation and Characterization of a genetic zebrafish model of SMA carrying the human SMN2 gene

BACKGROUND: Animal models of human diseases are essential as they allow analysis of the disease process at the cellular level and can advance therapeutics by serving as a tool for drug screening and target validation. Here we report the development of a complete genetic model of spinal muscular atro...

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Autores principales: Hao, Le T, Burghes, Arthur HM, Beattie, Christine E
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080329/
https://ncbi.nlm.nih.gov/pubmed/21443782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-24
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