Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

BACKGROUND: The β-amyloid precursor protein (APP) and the related β-amyloid precursor-like proteins (APLPs) undergo complex proteolytic processing giving rise to several fragments. Whereas it is well established that Aβ accumulation is a central trigger for Alzheimer's disease, the physiologica...

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Bibliografske podrobnosti
Main Authors: Aydin, Dorothee, Filippov, Mikhail A, Tschäpe, Jakob-Andreas, Gretz, Norbert, Prinz, Marco, Eils, Roland, Brors, Benedikt, Müller, Ulrike C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080314/
https://ncbi.nlm.nih.gov/pubmed/21435241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-160
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