The Physiological Functions of the Amyloid Precursor Protein Gene Family

The amyloid precursor protein APP plays a key role in the pathogenesis of Alzheimer’s disease (AD), as proteolytical cleavage of APP gives rise to the Aß peptide which is deposited in the brains of Alzheimer patients. Despite this, our knowledge of the normal cell biological and physiological functi...

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Publicado no:Frontiers Research Topics
Main Authors: Ulrike C. Muller, Thomas Deller
Formato: Livro
Idioma:Inglês
Publicado em: Frontiers Media SA 2017
Assuntos:
RC321-571
Q1-390
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Amyloid precursor-like protein
learning and memory
neuroprotection
spines
synaptic plasticity
Alzheimers disease
animal model
synaptogenesis
synaptic adhesion
Amyloid precursor protein
Acesso em linha:https://directory.doabooks.org/handle/20.500.12854/56238
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