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Optimizing Non-natural Protein Function with Directed Evolution
Developing technologies such as unnatural amino acid mutagenesis, non-natural cofactor engineering, and computational design are generating proteins with novel functions; these proteins, however, often do not reach performance targets and would benefit from further optimization. Evolutionary methods...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080047/ https://ncbi.nlm.nih.gov/pubmed/21185770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.11.020 |
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