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Crystallization and preliminary X-ray crystallographic analysis of human quinolinate phosphoribosyltransferase

Quinolinate phosphoribosyltransferase (QPRTase) is a key NAD-biosynthetic enzyme which catalyzes the transfer of quinolinic acid to 5-phosphoribosyl-1-pyrophosphate, yielding nicotinic acid mononucleotide. Homo sapiens QPRTase (Hs-QPRTase) appeared as a hexamer during purification and the protein wa...

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Autors principals: Kang, Gil Bu, Kim, Mun-Kyoung, Youn, Hyung-Seop, An, Jun Yop, Lee, Jung-Gyu, Park, Kyoung Ryoung, Lee, Sung Hang, Kim, Yongseong, Fukuoka, Shin-Ichi, Eom, Soo Hyun
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079967/
https://ncbi.nlm.nih.gov/pubmed/21206019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110041011
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