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Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site
Pteridine reductase (PTR1) is a potential target for drug development against parasitic Trypanosoma and Leishmania species, protozoa that are responsible for a range of serious diseases found in tropical and subtropical parts of the world. As part of a structure-based approach to inhibitor developme...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079966/ https://ncbi.nlm.nih.gov/pubmed/21206018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430911004724X |
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