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The NZM2410-derived lupus susceptibility locus Sle2c1 increases TH17 polarization and induces nephritis in Fas-deficient mice
OBJECTIVE: Sle2 is a lupus susceptibility locus that has been linked toglomerulonephritis in the NZM2410mouse. Byitself, Sle2 does not induce any autoimmune pathology, but results into the accumulation of B1a cells. This study was designed to assess the contribution of Sle2 to autoimmune pathogenesi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079951/ https://ncbi.nlm.nih.gov/pubmed/21360506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30146 |
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