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The combination of two Sle2 lupus-susceptibility loci and Cdkn2c deficiency leads to T cell-mediated pathology in B6.Fas(lpr) mice
The NZM2410 Sle2c1 lupus susceptibility locus is responsible for the expansion of the B1a cell compartment and for the induction of T-cell induced renal and skin pathology on a CD95 deficient (Fas(lpr))-background. We have previously shown that deficiency in cyclin-dependent kinase inhibitor p18(INK...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752316/ https://ncbi.nlm.nih.gov/pubmed/23698709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2013.28 |
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