Antibodies generated from human immunoglobulin miniloci in transgenic mice.

One approach to the production of human monoclonal antibodies focusses on the creation of transgenic mice bearing human immunoglobulin gene miniloci. Whilst such loci undergo lymphoid-specific gene rearrangement, only a small proportion of mouse B cells express the human immunoglobulin chains; the m...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Wagner, S D, Williams, G T, Larson, T, Neuberger, M S, Kitamura, D, Rajewsky, K, Xian, J, Brüggemann, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1994
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8190629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.8.1389
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