Continuous Localized Monitoring of Plasmin Activity Identifies Differential and Regional Effects of the Serine Protease Inhibitor Aprotinin: Relevance to Antifibrinolytic Therapy

BACKGROUND: Antifibrinolytic therapy, such as the use of the serine protease inhibitor aprotinin, was a mainstay for hemostasis following cardiac surgery. However, aprotinin was empirically dosed, and while the pharmacological target was the inhibition of plasmin activity (PLact) this was never moni...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Reust, Daryl L., Dixon, Jennifer A., McKinney, Richard A., Patel, Risha K., Rivers, William T., Mukherjee, Rupak, Stroud, Robert E., Madden, Karen, Groves, Kevin, Rajopadhye, Milind, Reeves, Scott T., Abernathy, James H., Spinale, Francis G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079882/
https://ncbi.nlm.nih.gov/pubmed/21502925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31820b7df1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker