Effects of Aprotinin or Tranexamic Acid on Proteolytic / Cytokine Profiles in Infants Following Cardiac Surgery

OBJECTIVE: Following cardiopulmonary bypass (CPB), elaboration of cytokines, and subsequent interstitial proteases induction, such as matrix metalloproteinases (MMPs), can result in a complex postoperative course. The serine protease inhibitor, aprotinin, which has been used in congenital heart surg...

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Main Authors: Hsia, Tain-Yen, McQuinn, Tim C., Mukherjee, Rupak, Deardorff, Rachael L., Squires, Jerry E., Stroud, Robert E., Crawford, Fred A., Bradley, Scott M., Reeves, Scott T., Spinale, Francis G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100188/
https://ncbi.nlm.nih.gov/pubmed/20494037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2010.02.069
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