Aprotinin Exerts Differential and Dose Dependent Effects on Myocardial Contractility, Oxidative Stress and Cytokine Release Following Ischemia-Reperfusion

BACKGROUND: Cardiac surgery can result in LV ischemia and reperfusion (I/R), the release of cytokines such as tumor necrosis factor, and oxidative-stress with release of myeloperoxidase. While aprotinin has been used in cardiac surgery, the likely multiple effects of this serine protease inhibitor l...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: McEvoy, Matthew D., Taylor, Anna-Greta, Zavadzkas, Juozas A., Mains, Ira M., Ford, Rachael A., Stroud, Robert E., Jeffords, Laura B., Beck, Christy U., Reeves, Scott T., Spinale, Francis G.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675543/
https://ncbi.nlm.nih.gov/pubmed/18640335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2008.04.025
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires