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RHOB LINKS PDGF SIGNALING TO CELL MIGRATION BY COORDINATING ACTIVATION AND LOCALIZATION OF CDC42 AND RAC
The small GTPase RhoB regulates endocytic trafficking of receptor tyrosine kinases (RTKs) and the non-receptor kinases Src and Akt. While receptor–mediated endocytosis is critical for signaling processes driving cell migration, mechanisms that coordinate endocytosis with the propagation of migratory...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079809/ https://ncbi.nlm.nih.gov/pubmed/21344485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23069 |
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