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BK large conductance Ca(2+)-activated K(+) channel deficient mice are not resistant to hypotension and display reduced survival benefit following polymicrobial sepsis
Nitric oxide mediated activation of large conductance calcium-activated potassium (BK) channels is considered an important underlying mechanism of sepsis-induced hypotension. Indeed, the non-selective K channel inhibitor, tetraethylammonium chloride (TEA) has been proposed as a potential treatment t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079605/ https://ncbi.nlm.nih.gov/pubmed/21330953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31820860f5 |
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