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Distinct inflammatory signals have physiologically divergent effects on epigenetic regulation of Foxp3 expression and Treg function

Foxp3 expression in regulatory T cells (Treg) is required for development and suppressive function. How different inflammatory signals affect Foxp3 chromatin structure, expression, and Tregs plasticity are not completely known. In the present study, the Toll-like receptor 2 (TLR2) ligand peptidoglyc...

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Main Authors: Lal, Girdhari, Yin, Na, Xu, Jiangnan, Lin, Marvin, Bernd, Schroppel, Ding, Yaozhong, Marie, Isabelle, Levy, David E., Bromberg, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079560/
https://ncbi.nlm.nih.gov/pubmed/21219575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03389.x
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